Interações medicamentosas
Cefaclor + Plazomicin
Gravidade: Moderada
Cefaclor and Plazomicin: moderate interaction.
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Resumo
Plazomicin carries warnings for nephrotoxicity, ototoxicity and neuromuscular blockade. Cephalosporins have occasionally been associated with additive kidney injury when combined with aminoglycosides, although cefaclor has relatively low nephrotoxic potential.
O que esta interação significa em palavras simples
Cefaclor and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefaclor belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
Por que acontece
Additive nephrotoxic effects on the renal tubule.
O que fazer
Monitor serum creatinine and plazomicin concentrations during combined use, and adjust the plazomicin dose to renal function per labeling.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Cefaclor
- Bcg vaccine live + Cefaclor Moderada
- Cefaclor + Cholera vaccine Moderada
- Cefaclor + Kanamycin Moderada
- Cefaclor + Microbiota Moderada
- Cefaclor + Sodium picosulfate / magnesium oxide / anhydrous citric acid Moderada
- Cefaclor + Typhoid vaccine live Moderada
Outras interações de Plazomicin
- Cefadroxil + Plazomicin Moderada
- Cefalexin + Plazomicin Moderada
- Cefazolin + Plazomicin Moderada
- Cefditoren + Plazomicin Moderada
- Cefepime + Plazomicin Moderada
- Cefixime + Plazomicin Moderada
Perguntas frequentes
Can I take Cefaclor with Plazomicin?
MediHelp rates the interaction as moderate. Cefaclor and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin carries warnings for nephrotoxicity, ototoxicity and neuromuscular blockade. Cephalosporins have occasionally been associated with additive kidney injury when combined with aminoglycosides, although cefaclor has relatively low nephrotoxic potential.
How serious is the interaction between Cefaclor and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin concentrations during combined use, and adjust the plazomicin dose to renal function per labeling.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.
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