Interações medicamentosas
Ceftazidime + Sodium picosulfate / magnesium oxide / anhydrous citric acid
Gravidade: Moderada
Ceftazidime and Sodium picosulfate / magnesium oxide / anhydrous citric acid: moderate interaction.
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Resumo
Sodium picosulfate is a prodrug activated by colonic bacteria, so antibiotics that disrupt colonic flora may reduce its laxative effect. Parenteral ceftazidime reaches the colon less than oral antibiotics, but poor bowel cleansing before colonoscopy is possible.
O que esta interação significa em palavras simples
Ceftazidime and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Antibiotic suppression of colonic bacteria reduces conversion of picosulfate to its active metabolite.
O que fazer
Assess bowel preparation adequacy and consider additional or alternative cleansing if the preparation seems inadequate. Where possible, avoid starting antibiotics during the preparation period.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Ceftazidime
- Amikacin + Ceftazidime Moderada
- Ceftazidime + Cholera vaccine Moderada
- Ceftazidime + Dexamethasone-tobramycin Moderada
- Ceftazidime + Gentamicin Moderada
- Ceftazidime + Kanamycin Moderada
- Ceftazidime + Microbiota Moderada
Perguntas frequentes
Can I take Ceftazidime with Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates the interaction as moderate. Ceftazidime and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug activated by colonic bacteria, so antibiotics that disrupt colonic flora may reduce its laxative effect. Parenteral ceftazidime reaches the colon less than oral antibiotics, but poor bowel cleansing before colonoscopy is possible.
How serious is the interaction between Ceftazidime and Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess bowel preparation adequacy and consider additional or alternative cleansing if the preparation seems inadequate. Where possible, avoid starting antibiotics during the preparation period.
What other medicines interact with Ceftazidime?
MediHelp also lists interactions of Ceftazidime with, for example, Amikacin, Cholera vaccine, Dexamethasone-tobramycin. The full list is on the Ceftazidime page.
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