Interações medicamentosas
Chloroquine + Ziprasidone
Gravidade: Contraindicada
Chloroquine and Ziprasidone: contraindicated interaction.
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Resumo
Ziprasidone is known for QT prolongation and its labeling advises against use with other QT-prolonging drugs. Adding chloroquine increases the risk of torsades de pointes and sudden cardiac death.
O que esta interação significa em palavras simples
Chloroquine and Ziprasidone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Chloroquine belongs to Anti Parasitic; Ziprasidone belongs to Central Nervous System.
Por que acontece
Additive blockade of cardiac potassium channels leading to delayed repolarization.
O que fazer
Avoid the combination and use a different antipsychotic or antimalarial. Ziprasidone labeling lists other QT-prolonging drugs as contraindicated.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Chloroquine
- Chloroquine + Cisapride Contraindicada
- Chloroquine + Dofetilide Contraindicada
- Chloroquine + Dronedarone Contraindicada
- Chloroquine + Droperidol Contraindicada
- Chloroquine + Panobinostat Contraindicada
- Chloroquine + Pimozide Contraindicada
Outras interações de Ziprasidone
- Amiodarone + Ziprasidone Contraindicada
- Amitriptyline + Ziprasidone Contraindicada
- Arsenic trioxide + Ziprasidone Contraindicada
- Bedaquiline + Ziprasidone Contraindicada
- Citalopram + Ziprasidone Contraindicada
- Clarithromycin + Ziprasidone Contraindicada
Perguntas frequentes
Can I take Chloroquine with Ziprasidone?
MediHelp rates the interaction as contraindicated. Chloroquine and Ziprasidone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ziprasidone is known for QT prolongation and its labeling advises against use with other QT-prolonging drugs. Adding chloroquine increases the risk of torsades de pointes and sudden cardiac death.
How serious is the interaction between Chloroquine and Ziprasidone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a different antipsychotic or antimalarial. Ziprasidone labeling lists other QT-prolonging drugs as contraindicated.
What other medicines interact with Chloroquine?
MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.
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