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Interações medicamentosas

Chlorthalidone + Ergocalciferol

Gravidade: Moderada

Chlorthalidone and Ergocalciferol: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

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Resumo

Thiazide-type diuretics reduce urinary calcium excretion, and with vitamin D this may lead to hypercalcemia. The risk is greater with high vitamin D doses or in hypoparathyroidism and renal impairment.

O que esta interação significa em palavras simples

Chlorthalidone and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Chlorthalidone belongs to Cardiovascular; Ergocalciferol belongs to Musculoskeletal.

Nível de evidência: Moderate

Por que acontece

Chlorthalidone decreases renal calcium excretion, adding to the increased calcium absorption caused by vitamin D.

O que fazer

Monitor serum calcium, especially after starting or changing doses. Reduce vitamin D dose if hypercalcemia develops.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Chlorthalidone with Ergocalciferol?

MediHelp rates the interaction as moderate. Chlorthalidone and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazide-type diuretics reduce urinary calcium excretion, and with vitamin D this may lead to hypercalcemia. The risk is greater with high vitamin D doses or in hypoparathyroidism and renal impairment.

How serious is the interaction between Chlorthalidone and Ergocalciferol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium, especially after starting or changing doses. Reduce vitamin D dose if hypercalcemia develops.

What other medicines interact with Ergocalciferol?

MediHelp also lists interactions of Ergocalciferol with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Ergocalciferol page.

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