Interações medicamentosas
Cholera vaccine + Minocycline
Gravidade: Grave
Cholera vaccine and Minocycline: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
The oral live attenuated cholera vaccine relies on the vaccine strain colonising the gut, and antibiotics active against it can reduce the immune response. Minocycline may therefore make the vaccine less effective.
O que esta interação significa em palavras simples
Cholera vaccine and Minocycline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Antibacterial activity against the live attenuated Vibrio cholerae vaccine strain reduces colonisation and immunogenicity.
O que fazer
Do not give the vaccine to patients who have received systemic antibiotics in the preceding 14 days, and avoid antibiotics for a period after vaccination per labeling. Delay vaccination if needed.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Minocycline
- Acitretin + Minocycline Contraindicada
- Isotretinoin + Minocycline Contraindicada
- Methoxyflurane + Minocycline Grave
- Minocycline + Palovarotene Grave
- Minocycline + Pexidartinib Grave
- Minocycline + Strontium ranelate Grave
Perguntas frequentes
Can I take Cholera vaccine with Minocycline?
MediHelp rates the interaction as major. Cholera vaccine and Minocycline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. The oral live attenuated cholera vaccine relies on the vaccine strain colonising the gut, and antibiotics active against it can reduce the immune response. Minocycline may therefore make the vaccine less effective.
How serious is the interaction between Cholera vaccine and Minocycline?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the vaccine to patients who have received systemic antibiotics in the preceding 14 days, and avoid antibiotics for a period after vaccination per labeling. Delay vaccination if needed.
What other medicines interact with Minocycline?
MediHelp also lists interactions of Minocycline with, for example, Acitretin, Isotretinoin, Methoxyflurane. The full list is on the Minocycline page.
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