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Interações medicamentosas

Isotretinoin + Minocycline

Gravidade: Contraindicada

Isotretinoin and Minocycline: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Isotretinoin and tetracyclines such as minocycline can each cause raised intracranial pressure (pseudotumour cerebri). Used together they may lead to headache, visual disturbance and papilloedema.

O que esta interação significa em palavras simples

Isotretinoin and Minocycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Isotretinoin belongs to Dermatology; Minocycline belongs to Anti Bacterial.

Nível de evidência: Moderate

Por que acontece

Additive risk of idiopathic intracranial hypertension

O que fazer

Avoid combination; use a non-tetracycline antibiotic during isotretinoin therapy and urgently evaluate headache or visual changes.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Isotretinoin with Minocycline?

MediHelp rates the interaction as contraindicated. Isotretinoin and Minocycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Isotretinoin and tetracyclines such as minocycline can each cause raised intracranial pressure (pseudotumour cerebri). Used together they may lead to headache, visual disturbance and papilloedema.

How serious is the interaction between Isotretinoin and Minocycline?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combination; use a non-tetracycline antibiotic during isotretinoin therapy and urgently evaluate headache or visual changes.

What other medicines interact with Minocycline?

MediHelp also lists interactions of Minocycline with, for example, Acitretin, Cholera vaccine, Methoxyflurane. The full list is on the Minocycline page.

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