Interações medicamentosas
Cholestyramine + Oxytetracycline
Gravidade: Moderada
Cholestyramine and Oxytetracycline: moderate interaction.
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Resumo
Cholestyramine binds tetracyclines in the gut and reduces their absorption, risking subtherapeutic antibiotic levels and treatment failure.
O que esta interação significa em palavras simples
Cholestyramine and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cholestyramine belongs to Cardiovascular; Oxytetracycline belongs to Anti Bacterial.
Por que acontece
Resin binds oxytetracycline in the gut lumen, decreasing absorption.
O que fazer
Give oxytetracycline at least 2 hours before or 4 to 6 hours after cholestyramine. Monitor clinical response to the antibiotic.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Cholestyramine
Outras interações de Oxytetracycline
- Isotretinoin + Oxytetracycline Contraindicada
- Aluminum hydroxide + Oxytetracycline Moderada
- Ampicillin-sulbactam + Oxytetracycline Moderada
- Ampicillin + Oxytetracycline Moderada
- Atracurium + Oxytetracycline Moderada
- Bismuth subsalicylate + Oxytetracycline Moderada
Perguntas frequentes
Can I take Cholestyramine with Oxytetracycline?
MediHelp rates the interaction as moderate. Cholestyramine and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cholestyramine binds tetracyclines in the gut and reduces their absorption, risking subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Cholestyramine and Oxytetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oxytetracycline at least 2 hours before or 4 to 6 hours after cholestyramine. Monitor clinical response to the antibiotic.
What other medicines interact with Cholestyramine?
MediHelp also lists interactions of Cholestyramine with, for example, Cholic acid, Deferasirox, Leflunomide. The full list is on the Cholestyramine page.
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