Pular para o conteúdo

Interações medicamentosas

Ciprofloxacin + Magnesium

Gravidade: Grave

Ciprofloxacin and Magnesium: major interaction.

Última atualização

Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Magnesium-containing products bind oral ciprofloxacin in the gut and markedly reduce its absorption. This can cause subtherapeutic antibiotic levels and treatment failure or resistance.

O que esta interação significa em palavras simples

Ciprofloxacin and Magnesium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Ciprofloxacin belongs to Anti Bacterial; Magnesium belongs to Gastrointestinal Tract.

Nível de evidência: High

Por que acontece

Magnesium cations chelate ciprofloxacin, forming poorly absorbed complexes.

O que fazer

Give ciprofloxacin at least 2 hours before or 6 hours after magnesium products. Consider a non-chelating alternative if separation is not feasible.

O que perguntar ao farmacêutico

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Para assinantes do Pro+

Desbloqueie a página completa

Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Ciprofloxacin e Magnesium, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Experimente o Pro+ grátis por 14 dias na web. Sem cartão.

Perguntas frequentes

Can I take Ciprofloxacin with Magnesium?

MediHelp rates the interaction as major. Ciprofloxacin and Magnesium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium-containing products bind oral ciprofloxacin in the gut and markedly reduce its absorption. This can cause subtherapeutic antibiotic levels and treatment failure or resistance.

How serious is the interaction between Ciprofloxacin and Magnesium?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give ciprofloxacin at least 2 hours before or 6 hours after magnesium products. Consider a non-chelating alternative if separation is not feasible.

What other medicines interact with Magnesium?

MediHelp also lists interactions of Magnesium with, for example, Pancuronium, Rocuronium, Vecuronium. The full list is on the Magnesium page.

Monografias completas, posologia e verificador de interações no app MediHelp

Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.

Explorar de A a Z · Interações medicamentosas

Baixar o app Entrar