Interações medicamentosas
Amphotericin b deoxycholate + Magnesium
Gravidade: Moderada
Amphotericin b deoxycholate and Magnesium: moderate interaction.
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Resumo
Amphotericin B deoxycholate causes renal tubular injury that leads to urinary magnesium wasting and hypomagnesemia. Low magnesium can aggravate hypokalemia and predispose to arrhythmias, particularly in patients receiving prolonged therapy.
O que esta interação significa em palavras simples
Amphotericin b deoxycholate and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Amphotericin B damages the renal tubules and increases urinary excretion of magnesium and potassium.
O que fazer
Monitor serum magnesium and potassium regularly during amphotericin B therapy. Replace magnesium as needed to correct deficits.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Magnesium
- Ciprofloxacin + Magnesium Grave
- Magnesium + Pancuronium Grave
- Magnesium + Rocuronium Grave
- Magnesium + Vecuronium Grave
- Amikacin + Magnesium Moderada
- Atracurium + Magnesium Moderada
Perguntas frequentes
Can I take Amphotericin b deoxycholate with Magnesium?
MediHelp rates the interaction as moderate. Amphotericin b deoxycholate and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B deoxycholate causes renal tubular injury that leads to urinary magnesium wasting and hypomagnesemia. Low magnesium can aggravate hypokalemia and predispose to arrhythmias, particularly in patients receiving prolonged therapy.
How serious is the interaction between Amphotericin b deoxycholate and Magnesium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium and potassium regularly during amphotericin B therapy. Replace magnesium as needed to correct deficits.
What other medicines interact with Magnesium?
MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.
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