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Interações medicamentosas

Amikacin + Magnesium

Gravidade: Moderada

Amikacin and Magnesium: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Aminoglycosides cause renal magnesium wasting, which can lead to hypomagnesemia with prolonged therapy. Low magnesium may then compound electrolyte disturbances such as hypokalemia and hypocalcemia.

O que esta interação significa em palavras simples

Amikacin and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amikacin belongs to Anti Bacterial; Magnesium belongs to Gastrointestinal Tract.

Nível de evidência: Moderate

Por que acontece

Aminoglycoside tubular toxicity impairs renal magnesium reabsorption, increasing urinary loss.

O que fazer

Monitor serum magnesium, potassium and calcium during prolonged aminoglycoside courses. Replace magnesium as needed.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Amikacin with Magnesium?

MediHelp rates the interaction as moderate. Amikacin and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aminoglycosides cause renal magnesium wasting, which can lead to hypomagnesemia with prolonged therapy. Low magnesium may then compound electrolyte disturbances such as hypokalemia and hypocalcemia.

How serious is the interaction between Amikacin and Magnesium?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium, potassium and calcium during prolonged aminoglycoside courses. Replace magnesium as needed.

What other medicines interact with Magnesium?

MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.

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