Interações medicamentosas
Ciprofloxacin + Zinc
Gravidade: Moderada
Ciprofloxacin and Zinc: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Zinc binds ciprofloxacin in the gut and markedly reduces its absorption, which can lead to subtherapeutic antibiotic levels and treatment failure.
O que esta interação significa em palavras simples
Ciprofloxacin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ciprofloxacin belongs to Anti Bacterial; Zinc belongs to Gastrointestinal Tract.
Por que acontece
Chelation of ciprofloxacin by divalent zinc cations in the gastrointestinal tract, forming poorly absorbed complexes.
O que fazer
Give ciprofloxacin at least 2 hours before or 6 hours after zinc-containing products. Counsel patients about multivitamins and mineral supplements.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicada
- Ciprofloxacin + Fezolinetant Contraindicada
- Ciprofloxacin + Thioridazine Contraindicada
- Ciprofloxacin + Tizanidine Contraindicada
- Ciprofloxacin + Vandetanib Contraindicada
- Alosetron + Ciprofloxacin Grave
Outras interações de Zinc
- Alendronate + Zinc Moderada
- Baloxavir marboxil + Zinc Moderada
- Cefalexin + Zinc Moderada
- Delafloxacin + Zinc Moderada
- Dolutegravir + Zinc Moderada
- Doxycycline + Zinc Moderada
Perguntas frequentes
Can I take Ciprofloxacin with Zinc?
MediHelp rates the interaction as moderate. Ciprofloxacin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Zinc binds ciprofloxacin in the gut and markedly reduces its absorption, which can lead to subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Ciprofloxacin and Zinc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give ciprofloxacin at least 2 hours before or 6 hours after zinc-containing products. Counsel patients about multivitamins and mineral supplements.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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