Interações medicamentosas
Delafloxacin + Zinc
Gravidade: Moderada
Delafloxacin and Zinc: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Zinc binds oral delafloxacin in the gut and reduces its absorption, potentially causing subtherapeutic antibiotic levels and treatment failure.
O que esta interação significa em palavras simples
Delafloxacin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Delafloxacin belongs to Anti Bacterial; Zinc belongs to Gastrointestinal Tract.
Por que acontece
Chelation of delafloxacin by polyvalent metal cations reduces gastrointestinal absorption.
O que fazer
Take delafloxacin at least 2 hours before or 6 hours after zinc products. Consider the intravenous formulation if separation is not possible.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Delafloxacin
- Aluminum hydroxide + Delafloxacin Moderada
- Calcium carbonate + Delafloxacin Moderada
- Calcium + Delafloxacin Moderada
- Carbonyl iron + Delafloxacin Moderada
- Delafloxacin + Didanosine Moderada
- Delafloxacin + Ferrous fumarate Moderada
Outras interações de Zinc
- Alendronate + Zinc Moderada
- Baloxavir marboxil + Zinc Moderada
- Cefalexin + Zinc Moderada
- Ciprofloxacin + Zinc Moderada
- Dolutegravir + Zinc Moderada
- Doxycycline + Zinc Moderada
Perguntas frequentes
Can I take Delafloxacin with Zinc?
MediHelp rates the interaction as moderate. Delafloxacin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Zinc binds oral delafloxacin in the gut and reduces its absorption, potentially causing subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Delafloxacin and Zinc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take delafloxacin at least 2 hours before or 6 hours after zinc products. Consider the intravenous formulation if separation is not possible.
What other medicines interact with Delafloxacin?
MediHelp also lists interactions of Delafloxacin with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Delafloxacin page.
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