Interações medicamentosas
Baloxavir marboxil + Zinc
Gravidade: Moderada
Baloxavir marboxil and Zinc: moderate interaction.
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Resumo
Zinc supplements can bind baloxavir in the gut and reduce its absorption. This may lower antiviral concentrations and diminish efficacy against influenza.
O que esta interação significa em palavras simples
Baloxavir marboxil and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Baloxavir marboxil belongs to Anti Virals; Zinc belongs to Gastrointestinal Tract.
Por que acontece
Polyvalent zinc cations chelate baloxavir in the gastrointestinal tract, reducing absorption.
O que fazer
Avoid taking zinc-containing products with baloxavir and defer them until after the antiviral course where feasible. If they must be used, separate dosing as widely as practical.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Baloxavir marboxil
- Aluminum hydroxide + Baloxavir marboxil Moderada
- Baloxavir marboxil + Calcium Moderada
- Baloxavir marboxil + Calcium carbonate Moderada
- Baloxavir marboxil + Carbonyl iron Moderada
- Baloxavir marboxil + Ferrous fumarate Moderada
- Baloxavir marboxil + Ferrous gluconate Moderada
Outras interações de Zinc
- Alendronate + Zinc Moderada
- Cefalexin + Zinc Moderada
- Ciprofloxacin + Zinc Moderada
- Delafloxacin + Zinc Moderada
- Dolutegravir + Zinc Moderada
- Doxycycline + Zinc Moderada
Perguntas frequentes
Can I take Baloxavir marboxil with Zinc?
MediHelp rates the interaction as moderate. Baloxavir marboxil and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Zinc supplements can bind baloxavir in the gut and reduce its absorption. This may lower antiviral concentrations and diminish efficacy against influenza.
How serious is the interaction between Baloxavir marboxil and Zinc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid taking zinc-containing products with baloxavir and defer them until after the antiviral course where feasible. If they must be used, separate dosing as widely as practical.
What other medicines interact with Baloxavir marboxil?
MediHelp also lists interactions of Baloxavir marboxil with, for example, Aluminum hydroxide, Calcium, Calcium carbonate. The full list is on the Baloxavir marboxil page.
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