Interações medicamentosas
Citalopram + Methylene blue
Gravidade: Contraindicada
Citalopram and Methylene blue: contraindicated interaction.
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Resumo
Methylene blue inhibits MAO-A and, with SSRIs like citalopram, can cause severe serotonin syndrome. Reactions can include altered mental status, hyperthermia, seizures and neuromuscular abnormalities.
O que esta interação significa em palavras simples
Citalopram and Methylene blue are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Reversible MAO-A inhibition by methylene blue added to SSRI-mediated serotonin reuptake blockade.
O que fazer
Avoid unless methylene blue is needed for an emergency; then stop citalopram and monitor for CNS toxicity. Resume only after the labeled interval after the last methylene blue dose.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Citalopram
- Cisapride + Citalopram Contraindicada
- Citalopram + Dronedarone Contraindicada
- Citalopram + Escitalopram Contraindicada
- Citalopram + Isocarboxazid Contraindicada
- Citalopram + Phenelzine Contraindicada
- Citalopram + Pimozide Contraindicada
Perguntas frequentes
Can I take Citalopram with Methylene blue?
MediHelp rates the interaction as contraindicated. Citalopram and Methylene blue are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methylene blue inhibits MAO-A and, with SSRIs like citalopram, can cause severe serotonin syndrome. Reactions can include altered mental status, hyperthermia, seizures and neuromuscular abnormalities.
How serious is the interaction between Citalopram and Methylene blue?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unless methylene blue is needed for an emergency; then stop citalopram and monitor for CNS toxicity. Resume only after the labeled interval after the last methylene blue dose.
What other medicines interact with Citalopram?
MediHelp also lists interactions of Citalopram with, for example, Cisapride, Dronedarone, Escitalopram. The full list is on the Citalopram page.
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