Interações medicamentosas
Cortisone + Human papillomavirus vaccine
Gravidade: Moderada
Cortisone and Human papillomavirus vaccine: moderate interaction.
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Resumo
Systemic corticosteroids at higher than physiologic doses suppress immune function and may reduce the antibody response to vaccines. Protection after HPV vaccination may be lower in patients on sustained high-dose therapy.
O que esta interação significa em palavras simples
Cortisone and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Glucocorticoid-mediated suppression of lymphocyte function reduces vaccine immunogenicity.
O que fazer
Non-live HPV vaccine can be given to patients on corticosteroids. Where possible vaccinate when the dose is low or before starting prolonged high-dose therapy, and consider checking response.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Human papillomavirus vaccine
- Antithymocyte globulin equine + Human papillomavirus vaccine Moderada
- Antithymocyte globulin rabbit + Human papillomavirus vaccine Moderada
- Atidarsagene autotemcel + Human papillomavirus vaccine Moderada
- Belimumab + Human papillomavirus vaccine Moderada
- Cyclosporine + Human papillomavirus vaccine Moderada
- Elivaldogene autotemcel + Human papillomavirus vaccine Moderada
Perguntas frequentes
Can I take Cortisone with Human papillomavirus vaccine?
MediHelp rates the interaction as moderate. Cortisone and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids at higher than physiologic doses suppress immune function and may reduce the antibody response to vaccines. Protection after HPV vaccination may be lower in patients on sustained high-dose therapy.
How serious is the interaction between Cortisone and Human papillomavirus vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Non-live HPV vaccine can be given to patients on corticosteroids. Where possible vaccinate when the dose is low or before starting prolonged high-dose therapy, and consider checking response.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.
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