Interações medicamentosas
Belimumab + Human papillomavirus vaccine
Gravidade: Moderada
Belimumab and Human papillomavirus vaccine: moderate interaction.
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Resumo
Belimumab suppresses B-cell survival and may blunt the antibody response to HPV vaccination. Protection may therefore be lower than expected, although the vaccine is non-live and not unsafe.
O que esta interação significa em palavras simples
Belimumab and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Belimumab belongs to Miscellaneous; Human papillomavirus vaccine belongs to Miscellaneous.
Por que acontece
Pharmacodynamic antagonism: belimumab inhibits BLyS and reduces B-cell mediated humoral immune responses.
O que fazer
Where possible, complete HPV vaccination before starting belimumab. If given during therapy, do not withhold the vaccine, and consider checking response or revaccinating when immunosuppression is reduced.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Human papillomavirus vaccine
- Antithymocyte globulin equine + Human papillomavirus vaccine Moderada
- Antithymocyte globulin rabbit + Human papillomavirus vaccine Moderada
- Atidarsagene autotemcel + Human papillomavirus vaccine Moderada
- Cortisone + Human papillomavirus vaccine Moderada
- Cyclosporine + Human papillomavirus vaccine Moderada
- Elivaldogene autotemcel + Human papillomavirus vaccine Moderada
Outras interações de Belimumab
- Belimumab + Measles mumps and rubella vaccine Grave
- Abatacept + Belimumab Moderada
- Adalimumab + Belimumab Moderada
- Anakinra + Belimumab Moderada
- Anti-thymocyte + Belimumab Moderada
- Belimumab + Denosumab Moderada
Perguntas frequentes
Can I take Belimumab with Human papillomavirus vaccine?
MediHelp rates the interaction as moderate. Belimumab and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Belimumab suppresses B-cell survival and may blunt the antibody response to HPV vaccination. Protection may therefore be lower than expected, although the vaccine is non-live and not unsafe.
How serious is the interaction between Belimumab and Human papillomavirus vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where possible, complete HPV vaccination before starting belimumab. If given during therapy, do not withhold the vaccine, and consider checking response or revaccinating when immunosuppression is reduced.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.
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