Interações medicamentosas
Demeclocycline + Dicloxacillin
Gravidade: Moderada
Demeclocycline and Dicloxacillin: moderate interaction.
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Resumo
Bacteriostatic tetracyclines can reduce the killing effect of penicillins on bacteria that need active growth. Evidence is mostly in vitro and from older reports, but it may matter in serious infections.
O que esta interação significa em palavras simples
Demeclocycline and Dicloxacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Tetracycline-induced inhibition of bacterial growth reduces the activity of cell-wall-active beta-lactams.
O que fazer
Avoid combining in serious infections that need bactericidal therapy. If unavoidable, monitor clinical response closely.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Dicloxacillin
- Dicloxacillin + Phenindione Grave
- Atogepant + Dicloxacillin Moderada
- Axitinib + Dicloxacillin Moderada
- Bcg vaccine live + Dicloxacillin Moderada
- Cholera vaccine + Dicloxacillin Moderada
- Dicloxacillin + Doxycycline Moderada
Perguntas frequentes
Can I take Demeclocycline with Dicloxacillin?
MediHelp rates the interaction as moderate. Demeclocycline and Dicloxacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bacteriostatic tetracyclines can reduce the killing effect of penicillins on bacteria that need active growth. Evidence is mostly in vitro and from older reports, but it may matter in serious infections.
How serious is the interaction between Demeclocycline and Dicloxacillin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining in serious infections that need bactericidal therapy. If unavoidable, monitor clinical response closely.
What other medicines interact with Dicloxacillin?
MediHelp also lists interactions of Dicloxacillin with, for example, Phenindione, Atogepant, Axitinib. The full list is on the Dicloxacillin page.
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