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Interações medicamentosas

Demeclocycline + Dicloxacillin

Gravidade: Moderada

Demeclocycline and Dicloxacillin: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Bacteriostatic tetracyclines can reduce the killing effect of penicillins on bacteria that need active growth. Evidence is mostly in vitro and from older reports, but it may matter in serious infections.

O que esta interação significa em palavras simples

Demeclocycline and Dicloxacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Nível de evidência: Low

Por que acontece

Tetracycline-induced inhibition of bacterial growth reduces the activity of cell-wall-active beta-lactams.

O que fazer

Avoid combining in serious infections that need bactericidal therapy. If unavoidable, monitor clinical response closely.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Demeclocycline with Dicloxacillin?

MediHelp rates the interaction as moderate. Demeclocycline and Dicloxacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bacteriostatic tetracyclines can reduce the killing effect of penicillins on bacteria that need active growth. Evidence is mostly in vitro and from older reports, but it may matter in serious infections.

How serious is the interaction between Demeclocycline and Dicloxacillin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining in serious infections that need bactericidal therapy. If unavoidable, monitor clinical response closely.

What other medicines interact with Dicloxacillin?

MediHelp also lists interactions of Dicloxacillin with, for example, Phenindione, Atogepant, Axitinib. The full list is on the Dicloxacillin page.

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