Interações medicamentosas
Docusate + Mineral oil
Gravidade: Moderada
Docusate and Mineral oil: moderate interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Docusate is a surfactant that may increase absorption of mineral oil from the gut. Absorbed mineral oil can deposit in tissues and, rarely, cause lipoid pneumonia or granulomas, so the combination is generally discouraged.
O que esta interação significa em palavras simples
Docusate and Mineral oil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Docusate belongs to Gastrointestinal Tract; Mineral oil belongs to Gastrointestinal Tract.
Por que acontece
Docusate's surfactant action emulsifies mineral oil and enhances its intestinal absorption.
O que fazer
Avoid combining the two laxatives. Use another stool softener or laxative if mineral oil is needed, especially in patients at risk of aspiration.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Mineral oil
Perguntas frequentes
Can I take Docusate with Mineral oil?
MediHelp rates the interaction as moderate. Docusate and Mineral oil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Docusate is a surfactant that may increase absorption of mineral oil from the gut. Absorbed mineral oil can deposit in tissues and, rarely, cause lipoid pneumonia or granulomas, so the combination is generally discouraged.
How serious is the interaction between Docusate and Mineral oil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining the two laxatives. Use another stool softener or laxative if mineral oil is needed, especially in patients at risk of aspiration.
What other medicines interact with Mineral oil?
MediHelp also lists interactions of Mineral oil with, for example, Vitamin k1, Beta carotene, Cholecalciferol. The full list is on the Mineral oil page.
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