Interações medicamentosas
Mineral oil + Vitamin k1
Gravidade: Moderada
Mineral oil and Vitamin k1: moderate interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Chronic mineral oil use can reduce absorption of phytonadione and other fat-soluble vitamins, which may lead to hypoprothrombinemia and bleeding in susceptible patients, such as those on anticoagulants or with poor intake.
O que esta interação significa em palavras simples
Mineral oil and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Mineral oil belongs to Gastrointestinal Tract; Vitamin k1 belongs to Cardiovascular.
Por que acontece
Mineral oil dissolves vitamin K in the gut lumen and carries it out in the stool, reducing absorption.
O que fazer
Avoid regular mineral oil use in patients dependent on vitamin K status. Monitor INR if the patient is on warfarin or has risk factors for deficiency.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Mineral oil
Outras interações de Vitamin k1
- Vitamin k1 + Warfarin Grave
- Cholestyramine + Vitamin k1 Moderada
- Colestipol + Vitamin k1 Moderada
- Ketorolac intranasal + Vitamin k1 Moderada
- Orlistat + Vitamin k1 Moderada
- Aescin + Vitamin k1 Leve
Perguntas frequentes
Can I take Mineral oil with Vitamin k1?
MediHelp rates the interaction as moderate. Mineral oil and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chronic mineral oil use can reduce absorption of phytonadione and other fat-soluble vitamins, which may lead to hypoprothrombinemia and bleeding in susceptible patients, such as those on anticoagulants or with poor intake.
How serious is the interaction between Mineral oil and Vitamin k1?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular mineral oil use in patients dependent on vitamin K status. Monitor INR if the patient is on warfarin or has risk factors for deficiency.
What other medicines interact with Mineral oil?
MediHelp also lists interactions of Mineral oil with, for example, Docusate, Beta carotene, Cholecalciferol. The full list is on the Mineral oil page.
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