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Interações medicamentosas

Cholecalciferol + Mineral oil

Gravidade: Leve

Cholecalciferol and Mineral oil: minor interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Oral mineral oil can dissolve fat-soluble vitamins in the gut lumen and carry them out in the stool. Regular use may lower absorption of cholecalciferol and contribute to vitamin D insufficiency.

O que esta interação significa em palavras simples

Cholecalciferol and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Cholecalciferol belongs to Musculoskeletal; Mineral oil belongs to Gastrointestinal Tract.

Nível de evidência: Moderate

Por que acontece

Mineral oil is a non-absorbable lipophilic substance that sequesters fat-soluble vitamins and reduces their intestinal absorption.

O que fazer

Avoid regular long-term mineral oil use in patients who need vitamin D, or separate the doses by several hours. Check 25-hydroxyvitamin D if use is prolonged.

O que perguntar ao farmacêutico

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Cholecalciferol with Mineral oil?

MediHelp rates the interaction as minor. Cholecalciferol and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral mineral oil can dissolve fat-soluble vitamins in the gut lumen and carry them out in the stool. Regular use may lower absorption of cholecalciferol and contribute to vitamin D insufficiency.

How serious is the interaction between Cholecalciferol and Mineral oil?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular long-term mineral oil use in patients who need vitamin D, or separate the doses by several hours. Check 25-hydroxyvitamin D if use is prolonged.

What other medicines interact with Cholecalciferol?

MediHelp also lists interactions of Cholecalciferol with, for example, Digoxin, Aluminum hydroxide, Calcium acetate. The full list is on the Cholecalciferol page.

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