Interações medicamentosas
Enoxaparin + Ketorolac
Gravidade: Contraindicada
Enoxaparin and Ketorolac: contraindicated interaction.
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Resumo
Ketorolac inhibits platelets and can cause GI bleeding, and enoxaparin is an anticoagulant, so serious hemorrhage including spinal or epidural hematoma is more likely. Ketorolac labeling contraindicates use in patients at risk of bleeding.
O que esta interação significa em palavras simples
Enoxaparin and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Enoxaparin belongs to Cardiovascular; Ketorolac belongs to Musculoskeletal.
Por que acontece
Additive hemostatic impairment through antiplatelet NSAID effect and low molecular weight heparin anti-Xa activity.
O que fazer
Avoid ketorolac in patients receiving enoxaparin and choose a non-NSAID analgesic; if exposure occurs, monitor for bleeding and neurologic signs after neuraxial procedures.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Ketorolac
- Aceclofenac + Ketorolac Contraindicada
- Acemetacin + Ketorolac Contraindicada
- Acetylsalicylic acid + Ketorolac Contraindicada
- Apixaban + Ketorolac Contraindicada
- Argatroban + Ketorolac Contraindicada
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicada
Outras interações de Enoxaparin
- Defibrotide + Enoxaparin Contraindicada
- Enoxaparin + Mifepristone Contraindicada
- Abciximab + Enoxaparin Grave
- Aceclofenac + Enoxaparin Grave
- Acetylsalicylic acid + Enoxaparin Grave
- Alteplase + Enoxaparin Grave
Perguntas frequentes
Can I take Enoxaparin with Ketorolac?
MediHelp rates the interaction as contraindicated. Enoxaparin and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac inhibits platelets and can cause GI bleeding, and enoxaparin is an anticoagulant, so serious hemorrhage including spinal or epidural hematoma is more likely. Ketorolac labeling contraindicates use in patients at risk of bleeding.
How serious is the interaction between Enoxaparin and Ketorolac?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ketorolac in patients receiving enoxaparin and choose a non-NSAID analgesic; if exposure occurs, monitor for bleeding and neurologic signs after neuraxial procedures.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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