Interações medicamentosas
Ergotamine + Sumatriptan
Gravidade: Contraindicada
Ergotamine and Sumatriptan: contraindicated interaction.
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Resumo
Ergotamine and sumatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.
O que esta interação significa em palavras simples
Ergotamine and Sumatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ergotamine belongs to Central Nervous System; Sumatriptan belongs to Central Nervous System.
Por que acontece
Additive vasoconstriction through serotonin receptors
O que fazer
Do not administer within 24 hours of each other.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Sumatriptan
- Almotriptan + Sumatriptan Contraindicada
- Dihydroergotamine intranasal + Sumatriptan Contraindicada
- Dihydroergotamine + Sumatriptan Contraindicada
- Eletriptan + Sumatriptan Contraindicada
- Ergoloid mesylates + Sumatriptan Contraindicada
- Frovatriptan + Sumatriptan Contraindicada
Outras interações de Ergotamine
- Almotriptan + Ergotamine Contraindicada
- Atazanavir + Ergotamine Contraindicada
- Clarithromycin + Ergotamine Contraindicada
- Cobicistat + Ergotamine Contraindicada
- Darunavir + Ergotamine Contraindicada
- Dihydroergotamine intranasal + Ergotamine Contraindicada
Perguntas frequentes
Can I take Ergotamine with Sumatriptan?
MediHelp rates the interaction as contraindicated. Ergotamine and Sumatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ergotamine and sumatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.
How serious is the interaction between Ergotamine and Sumatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer within 24 hours of each other.
What other medicines interact with Sumatriptan?
MediHelp also lists interactions of Sumatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Sumatriptan page.
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