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Interações medicamentosas

Etanercept + Rubella vaccine

Gravidade: Contraindicada

Etanercept and Rubella vaccine: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Rubella vaccine is live attenuated and may replicate excessively in a patient on TNF blockade. This raises the risk of vaccine-strain disease. Immune response may be reduced.

O que esta interação significa em palavras simples

Etanercept and Rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: Moderate

Por que acontece

TNF inhibition weakens immune control of live attenuated virus.

O que fazer

Avoid during etanercept therapy. Vaccinate at least 4 weeks before starting treatment, or after adequate washout.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Etanercept with Rubella vaccine?

MediHelp rates the interaction as contraindicated. Etanercept and Rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rubella vaccine is live attenuated and may replicate excessively in a patient on TNF blockade. This raises the risk of vaccine-strain disease. Immune response may be reduced.

How serious is the interaction between Etanercept and Rubella vaccine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during etanercept therapy. Vaccinate at least 4 weeks before starting treatment, or after adequate washout.

What other medicines interact with Etanercept?

MediHelp also lists interactions of Etanercept with, for example, Bcg vaccine live, Golimumab, Measles mumps and rubella vaccine. The full list is on the Etanercept page.

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