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Interações medicamentosas

Etanercept + Measles vaccine

Gravidade: Contraindicada

Etanercept and Measles vaccine: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Measles vaccine is live attenuated, and TNF blockade may allow uncontrolled vaccine virus replication. Disseminated vaccine-strain infection is a theoretical risk. Immune response may also be reduced.

O que esta interação significa em palavras simples

Etanercept and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: Moderate

Por que acontece

Immunosuppression from TNF inhibition reduces control of live attenuated virus replication.

O que fazer

Avoid live measles vaccine during etanercept therapy. Vaccinate at least 4 weeks before starting treatment where possible, or after an adequate washout, and consider immunoglobulin if exposed.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Etanercept with Measles vaccine?

MediHelp rates the interaction as contraindicated. Etanercept and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated, and TNF blockade may allow uncontrolled vaccine virus replication. Disseminated vaccine-strain infection is a theoretical risk. Immune response may also be reduced.

How serious is the interaction between Etanercept and Measles vaccine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live measles vaccine during etanercept therapy. Vaccinate at least 4 weeks before starting treatment where possible, or after an adequate washout, and consider immunoglobulin if exposed.

What other medicines interact with Etanercept?

MediHelp also lists interactions of Etanercept with, for example, Bcg vaccine live, Golimumab, Measles mumps and rubella vaccine. The full list is on the Etanercept page.

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