Interações medicamentosas
Etanercept + Golimumab
Gravidade: Contraindicada
Etanercept and Golimumab: contraindicated interaction.
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Resumo
Both agents are TNF-alpha inhibitors, so combining them duplicates therapy without added benefit. Studies of TNF blocker combinations showed more serious infections and adverse events.
O que esta interação significa em palavras simples
Etanercept and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Etanercept belongs to Musculoskeletal; Golimumab belongs to Musculoskeletal.
Por que acontece
Duplicate TNF-alpha blockade causing additive immunosuppression.
O que fazer
Do not combine two TNF inhibitors. Use a single agent and switch to another class if response is inadequate.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Golimumab
- Bcg vaccine live + Golimumab Contraindicada
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicada
- Golimumab + Measles mumps and rubella vaccine Contraindicada
- Golimumab + Measles mumps and rubella vaccine live Contraindicada
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicada
- Golimumab + Measles vaccine Contraindicada
Outras interações de Etanercept
- Bcg vaccine live + Etanercept Contraindicada
- Etanercept + Measles mumps and rubella vaccine Contraindicada
- Etanercept + Measles mumps and rubella vaccine live Contraindicada
- Etanercept + Measles mumps rubella and varicella vaccine live Contraindicada
- Etanercept + Measles vaccine Contraindicada
- Etanercept + Rubella vaccine Contraindicada
Perguntas frequentes
Can I take Etanercept with Golimumab?
MediHelp rates the interaction as contraindicated. Etanercept and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents are TNF-alpha inhibitors, so combining them duplicates therapy without added benefit. Studies of TNF blocker combinations showed more serious infections and adverse events.
How serious is the interaction between Etanercept and Golimumab?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine two TNF inhibitors. Use a single agent and switch to another class if response is inadequate.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Golimumab page.
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