Interações medicamentosas
Ethanol + Tinidazole
Gravidade: Grave
Ethanol and Tinidazole: major interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Drinking alcohol during tinidazole therapy can cause a disulfiram-like reaction with flushing, nausea, vomiting, abdominal cramps, headache and palpitations. This effect can persist after the last tinidazole dose.
O que esta interação significa em palavras simples
Ethanol and Tinidazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Proposed inhibition of aldehyde dehydrogenase, causing acetaldehyde accumulation, though the mechanism is debated.
O que fazer
Advise patients to avoid alcohol and ethanol-containing products during treatment and for 3 days after the last dose. Counsel on hidden sources such as some liquid medicines.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Tinidazole
- Disulfiram + Tinidazole Contraindicada
- Fexinidazole + Tinidazole Grave
- Lopinavir + Tinidazole Grave
- Nilotinib + Tinidazole Grave
- Ritonavir + Tinidazole Grave
- Amiodarone + Tinidazole Moderada
Perguntas frequentes
Can I take Ethanol with Tinidazole?
MediHelp rates the interaction as major. Ethanol and Tinidazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Drinking alcohol during tinidazole therapy can cause a disulfiram-like reaction with flushing, nausea, vomiting, abdominal cramps, headache and palpitations. This effect can persist after the last tinidazole dose.
How serious is the interaction between Ethanol and Tinidazole?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid alcohol and ethanol-containing products during treatment and for 3 days after the last dose. Counsel on hidden sources such as some liquid medicines.
What other medicines interact with Tinidazole?
MediHelp also lists interactions of Tinidazole with, for example, Disulfiram, Fexinidazole, Lopinavir. The full list is on the Tinidazole page.
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