Pular para o conteúdo

Interações medicamentosas

Factor ix + Tranexamic acid

Gravidade: Grave

Factor ix and Tranexamic acid: major interaction.

Última atualização

Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Factor IX products can be thrombogenic, particularly prothrombin complex concentrates, and tranexamic acid blocks fibrinolysis. Using both together increases the chance of venous or arterial thrombosis.

O que esta interação significa em palavras simples

Factor ix and Tranexamic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Factor ix belongs to Cardiovascular; Tranexamic acid belongs to Cardiovascular.

Nível de evidência: Moderate

Por que acontece

Additive procoagulant effects: antifibrinolysis plus factor replacement

O que fazer

Use together only when needed (e.g. dental procedures in haemophilia B), at lowest effective doses with thrombosis monitoring.

O que perguntar ao farmacêutico

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Para assinantes do Pro+

Desbloqueie a página completa

Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Factor ix e Tranexamic acid, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Experimente o Pro+ grátis por 7 dias na web. Sem cartão.

Perguntas frequentes

Can I take Factor ix with Tranexamic acid?

MediHelp rates the interaction as major. Factor ix and Tranexamic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Factor IX products can be thrombogenic, particularly prothrombin complex concentrates, and tranexamic acid blocks fibrinolysis. Using both together increases the chance of venous or arterial thrombosis.

How serious is the interaction between Factor ix and Tranexamic acid?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use together only when needed (e.g. dental procedures in haemophilia B), at lowest effective doses with thrombosis monitoring.

What other medicines interact with Tranexamic acid?

MediHelp also lists interactions of Tranexamic acid with, for example, Dienogest / estradiol valerate, Ethinyl estradiol-drospirenone, Ethinyl estradiol-levonorgestrel. The full list is on the Tranexamic acid page.

Monografias completas, posologia e verificador de interações no app MediHelp

Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.

Explorar de A a Z · Interações medicamentosas

Baixar o app Entrar