Interações medicamentosas
Factor ix + Tranexamic acid
Gravidade: Grave
Factor ix and Tranexamic acid: major interaction.
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Resumo
Factor IX products can be thrombogenic, particularly prothrombin complex concentrates, and tranexamic acid blocks fibrinolysis. Using both together increases the chance of venous or arterial thrombosis.
O que esta interação significa em palavras simples
Factor ix and Tranexamic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Factor ix belongs to Cardiovascular; Tranexamic acid belongs to Cardiovascular.
Por que acontece
Additive procoagulant effects: antifibrinolysis plus factor replacement
O que fazer
Use together only when needed (e.g. dental procedures in haemophilia B), at lowest effective doses with thrombosis monitoring.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Tranexamic acid
- Dienogest / estradiol valerate + Tranexamic acid Contraindicada
- Ethinyl estradiol-drospirenone + Tranexamic acid Contraindicada
- Ethinyl estradiol-levonorgestrel + Tranexamic acid Contraindicada
- Ethinyl estradiol-norgestimate + Tranexamic acid Contraindicada
- Ethinylestradiol + Tranexamic acid Contraindicada
- Mestranol + Tranexamic acid Contraindicada
Outras interações de Factor ix
Perguntas frequentes
Can I take Factor ix with Tranexamic acid?
MediHelp rates the interaction as major. Factor ix and Tranexamic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Factor IX products can be thrombogenic, particularly prothrombin complex concentrates, and tranexamic acid blocks fibrinolysis. Using both together increases the chance of venous or arterial thrombosis.
How serious is the interaction between Factor ix and Tranexamic acid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use together only when needed (e.g. dental procedures in haemophilia B), at lowest effective doses with thrombosis monitoring.
What other medicines interact with Tranexamic acid?
MediHelp also lists interactions of Tranexamic acid with, for example, Dienogest / estradiol valerate, Ethinyl estradiol-drospirenone, Ethinyl estradiol-levonorgestrel. The full list is on the Tranexamic acid page.
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