Interações medicamentosas
Dienogest / estradiol valerate + Tranexamic acid
Gravidade: Contraindicada
Dienogest / estradiol valerate and Tranexamic acid: contraindicated interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Oral tranexamic acid is antifibrinolytic and estrogen-containing contraceptives are prothrombotic. Together they raise the risk of venous and arterial thrombosis, and oral tranexamic acid labeling contraindicates use with combined hormonal contraceptives.
O que esta interação significa em palavras simples
Dienogest / estradiol valerate and Tranexamic acid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Additive prothrombotic effects of fibrinolysis inhibition and estrogen-induced increases in clotting factors.
O que fazer
Avoid the combination; use non-hormonal or progestin-only contraception while taking tranexamic acid, or choose another heavy-bleeding treatment.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Dienogest / estradiol valerate e Tranexamic acid, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Tranexamic acid
- Ethinyl estradiol-drospirenone + Tranexamic acid Contraindicada
- Ethinyl estradiol-levonorgestrel + Tranexamic acid Contraindicada
- Ethinyl estradiol-norgestimate + Tranexamic acid Contraindicada
- Ethinylestradiol + Tranexamic acid Contraindicada
- Mestranol + Tranexamic acid Contraindicada
- Alteplase + Tranexamic acid Grave
Perguntas frequentes
Can I take Dienogest / estradiol valerate with Tranexamic acid?
MediHelp rates the interaction as contraindicated. Dienogest / estradiol valerate and Tranexamic acid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oral tranexamic acid is antifibrinolytic and estrogen-containing contraceptives are prothrombotic. Together they raise the risk of venous and arterial thrombosis, and oral tranexamic acid labeling contraindicates use with combined hormonal contraceptives.
How serious is the interaction between Dienogest / estradiol valerate and Tranexamic acid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; use non-hormonal or progestin-only contraception while taking tranexamic acid, or choose another heavy-bleeding treatment.
What other medicines interact with Tranexamic acid?
MediHelp also lists interactions of Tranexamic acid with, for example, Ethinyl estradiol-drospirenone, Ethinyl estradiol-levonorgestrel, Ethinyl estradiol-norgestimate. The full list is on the Tranexamic acid page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
