Interações medicamentosas
Ferric oxyhydroxide + Levothyroxine
Gravidade: Moderada
Ferric oxyhydroxide and Levothyroxine: moderate interaction.
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Resumo
Iron compounds bind levothyroxine in the gut and reduce its absorption, which may raise TSH and cause hypothyroid symptoms.
O que esta interação significa em palavras simples
Ferric oxyhydroxide and Levothyroxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferric oxyhydroxide belongs to Gastrointestinal Tract; Levothyroxine belongs to Endocrine.
Por que acontece
Formation of insoluble complexes between iron and levothyroxine in the gastrointestinal tract.
O que fazer
Give levothyroxine at least 4 hours before ferric oxyhydroxide and monitor TSH.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Ferric oxyhydroxide
Outras interações de Levothyroxine
Perguntas frequentes
Can I take Ferric oxyhydroxide with Levothyroxine?
MediHelp rates the interaction as moderate. Ferric oxyhydroxide and Levothyroxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron compounds bind levothyroxine in the gut and reduce its absorption, which may raise TSH and cause hypothyroid symptoms.
How serious is the interaction between Ferric oxyhydroxide and Levothyroxine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give levothyroxine at least 4 hours before ferric oxyhydroxide and monitor TSH.
What other medicines interact with Ferric oxyhydroxide?
MediHelp also lists interactions of Ferric oxyhydroxide with, for example, Doxycycline, Acetylsalicylic acid, Cefalexin. The full list is on the Ferric oxyhydroxide page.
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