Interações medicamentosas
Ibutilide + Levofloxacin
Gravidade: Contraindicada
Ibutilide and Levofloxacin: contraindicated interaction.
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Resumo
Ibutilide is a class III antiarrhythmic with a substantial risk of torsades de pointes. Levofloxacin further prolongs repolarization, making a serious ventricular arrhythmia more likely.
O que esta interação significa em palavras simples
Ibutilide and Levofloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ibutilide belongs to Cardiovascular; Levofloxacin belongs to Anti Bacterial.
Por que acontece
Additive potassium channel blockade causing QT prolongation.
O que fazer
Avoid giving levofloxacin to patients receiving ibutilide and choose a non-QT-prolonging antibiotic. If ibutilide is being used for cardioversion, defer fluoroquinolone administration until after the procedure and monitoring period.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Levofloxacin
- Dronedarone + Levofloxacin Contraindicada
- Levofloxacin + Thioridazine Contraindicada
- Levofloxacin + Vandetanib Contraindicada
- Levofloxacin + Ziprasidone Contraindicada
- Adagrasib + Levofloxacin Grave
- Amiodarone + Levofloxacin Grave
Outras interações de Ibutilide
- Amiodarone + Ibutilide Contraindicada
- Amisulpride + Ibutilide Contraindicada
- Chlorpromazine + Ibutilide Contraindicada
- Clarithromycin + Ibutilide Contraindicada
- Desipramine + Ibutilide Contraindicada
- Dolasetron + Ibutilide Contraindicada
Perguntas frequentes
Can I take Ibutilide with Levofloxacin?
MediHelp rates the interaction as contraindicated. Ibutilide and Levofloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ibutilide is a class III antiarrhythmic with a substantial risk of torsades de pointes. Levofloxacin further prolongs repolarization, making a serious ventricular arrhythmia more likely.
How serious is the interaction between Ibutilide and Levofloxacin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving levofloxacin to patients receiving ibutilide and choose a non-QT-prolonging antibiotic. If ibutilide is being used for cardioversion, defer fluoroquinolone administration until after the procedure and monitoring period.
What other medicines interact with Levofloxacin?
MediHelp also lists interactions of Levofloxacin with, for example, Dronedarone, Thioridazine, Vandetanib. The full list is on the Levofloxacin page.
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