Interações medicamentosas
Insulin aspart protamine / insulin aspart + Rosiglitazone
Gravidade: Grave
Insulin aspart protamine / insulin aspart and Rosiglitazone: major interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Rosiglitazone and insulin additively lower glucose, which can cause hypoglycemia. The combination also increases the risk of fluid retention, edema and heart failure.
O que esta interação significa em palavras simples
Insulin aspart protamine / insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Additive glucose-lowering effects, and combined sodium and fluid retention from thiazolidinedione and insulin.
O que fazer
Monitor glucose and reduce insulin dose if hypoglycemia occurs. Watch for edema, weight gain and heart failure symptoms; labeling advises caution with this combination.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Insulin aspart protamine / insulin aspart e Rosiglitazone, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Rosiglitazone
Perguntas frequentes
Can I take Insulin aspart protamine / insulin aspart with Rosiglitazone?
MediHelp rates the interaction as major. Insulin aspart protamine / insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone and insulin additively lower glucose, which can cause hypoglycemia. The combination also increases the risk of fluid retention, edema and heart failure.
How serious is the interaction between Insulin aspart protamine / insulin aspart and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose and reduce insulin dose if hypoglycemia occurs. Watch for edema, weight gain and heart failure symptoms; labeling advises caution with this combination.
What other medicines interact with Rosiglitazone?
MediHelp also lists interactions of Rosiglitazone with, for example, Insulin aspart-insulin aspart protamine, Insulin aspart, Insulin degludec / insulin aspart. The full list is on the Rosiglitazone page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
