Interações medicamentosas
Iodine + Propylthiouracil
Gravidade: Moderada
Iodine and Propylthiouracil: moderate interaction.
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Resumo
Systemic iodine affects thyroid hormone production and release, so combining it with an antithyroid drug may lead to unpredictable thyroid control. Excess iodine can add to hypothyroid or goitrogenic effects.
O que esta interação significa em palavras simples
Iodine and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Iodine belongs to Dermatology; Propylthiouracil belongs to Endocrine.
Por que acontece
Excess iodide inhibits thyroid hormone release and synthesis, adding to thyroid peroxidase inhibition.
O que fazer
Monitor thyroid function and avoid unnecessary iodine supplements during propylthiouracil therapy unless used deliberately, for example before thyroid surgery.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Propylthiouracil
Outras interações de Iodine
- Iodine + Lithium Moderada
- Iodine + Methimazole Moderada
Perguntas frequentes
Can I take Iodine with Propylthiouracil?
MediHelp rates the interaction as moderate. Iodine and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic iodine affects thyroid hormone production and release, so combining it with an antithyroid drug may lead to unpredictable thyroid control. Excess iodine can add to hypothyroid or goitrogenic effects.
How serious is the interaction between Iodine and Propylthiouracil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor thyroid function and avoid unnecessary iodine supplements during propylthiouracil therapy unless used deliberately, for example before thyroid surgery.
What other medicines interact with Propylthiouracil?
MediHelp also lists interactions of Propylthiouracil with, for example, Carbamazepine, Clozapine, Methimazole. The full list is on the Propylthiouracil page.
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