Interações medicamentosas
Leflunomide + Measles vaccine
Gravidade: Contraindicada
Leflunomide and Measles vaccine: contraindicated interaction.
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Resumo
Measles vaccine contains live attenuated virus, which may cause disseminated vaccine-strain infection in a patient immunosuppressed by leflunomide. The vaccine response may also be inadequate.
O que esta interação significa em palavras simples
Leflunomide and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Impaired lymphocyte function reduces control of live attenuated virus replication.
O que fazer
Avoid live vaccines during leflunomide treatment and until drug elimination is confirmed; vaccinate before therapy.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Leflunomide
- Bcg vaccine live + Leflunomide Contraindicada
- Influenza virus vaccine quadrivalent intranasal + Leflunomide Contraindicada
- Leflunomide + Measles mumps and rubella vaccine live Contraindicada
- Leflunomide + Measles mumps rubella and varicella vaccine live Contraindicada
- Leflunomide + Smallpox vaccine live Contraindicada
- Alefacept + Leflunomide Grave
Perguntas frequentes
Can I take Leflunomide with Measles vaccine?
MediHelp rates the interaction as contraindicated. Leflunomide and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine contains live attenuated virus, which may cause disseminated vaccine-strain infection in a patient immunosuppressed by leflunomide. The vaccine response may also be inadequate.
How serious is the interaction between Leflunomide and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during leflunomide treatment and until drug elimination is confirmed; vaccinate before therapy.
What other medicines interact with Leflunomide?
MediHelp also lists interactions of Leflunomide with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Leflunomide page.
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