Interações medicamentosas
Lomustine + Measles vaccine
Gravidade: Contraindicada
Lomustine and Measles vaccine: contraindicated interaction.
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Resumo
Live measles vaccine can cause progressive or disseminated measles infection in patients immunosuppressed by lomustine. Vaccine response may also be inadequate.
O que esta interação significa em palavras simples
Lomustine and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Cytotoxic immunosuppression impairs control of live vaccine virus replication and reduces the immune response.
O que fazer
Avoid during lomustine therapy and defer until immune recovery, generally at least 3 months after chemotherapy ends. Consider immunoglobulin prophylaxis if exposed to measles.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Lomustine
- Adenovirus types 4 and 7 live + Lomustine Contraindicada
- Bcg vaccine live + Lomustine Contraindicada
- Influenza virus vaccine quadrivalent intranasal + Lomustine Contraindicada
- Lomustine + Measles mumps and rubella vaccine Contraindicada
- Lomustine + Measles mumps and rubella vaccine live Contraindicada
- Lomustine + Measles mumps rubella and varicella vaccine live Contraindicada
Perguntas frequentes
Can I take Lomustine with Measles vaccine?
MediHelp rates the interaction as contraindicated. Lomustine and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live measles vaccine can cause progressive or disseminated measles infection in patients immunosuppressed by lomustine. Vaccine response may also be inadequate.
How serious is the interaction between Lomustine and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during lomustine therapy and defer until immune recovery, generally at least 3 months after chemotherapy ends. Consider immunoglobulin prophylaxis if exposed to measles.
What other medicines interact with Lomustine?
MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.
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