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Interações medicamentosas

Lomustine + Measles mumps rubella and varicella vaccine live

Gravidade: Contraindicada

Lomustine and Measles mumps rubella and varicella vaccine live: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

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Resumo

The combined live MMRV vaccine carries a risk of disseminated vaccine-strain infection in patients immunosuppressed by lomustine, and immunogenicity is reduced.

O que esta interação significa em palavras simples

Lomustine and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: High

Por que acontece

Cytotoxic immunosuppression impairs control of live vaccine virus replication and reduces the immune response.

O que fazer

Avoid during lomustine therapy and until immune recovery, generally at least 3 months after treatment. Revaccinate once immune function is restored.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Lomustine with Measles mumps rubella and varicella vaccine live?

MediHelp rates the interaction as contraindicated. Lomustine and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The combined live MMRV vaccine carries a risk of disseminated vaccine-strain infection in patients immunosuppressed by lomustine, and immunogenicity is reduced.

How serious is the interaction between Lomustine and Measles mumps rubella and varicella vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during lomustine therapy and until immune recovery, generally at least 3 months after treatment. Revaccinate once immune function is restored.

What other medicines interact with Lomustine?

MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.

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