Interações medicamentosas
Lycopus + Propylthiouracil
Gravidade: Moderada
Lycopus and Propylthiouracil: moderate interaction.
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Resumo
Lycopus (bugleweed) has antithyroid activity and may add to the effect of propylthiouracil, increasing the risk of hypothyroidism. Evidence is limited to traditional use and small studies.
O que esta interação significa em palavras simples
Lycopus and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Additive antithyroid effect through reduced thyroid stimulation and peripheral T4 to T3 conversion.
O que fazer
Avoid combining the herb with antithyroid drugs unless supervised. Monitor TSH and free T4 if both are used.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Propylthiouracil
Perguntas frequentes
Can I take Lycopus with Propylthiouracil?
MediHelp rates the interaction as moderate. Lycopus and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lycopus (bugleweed) has antithyroid activity and may add to the effect of propylthiouracil, increasing the risk of hypothyroidism. Evidence is limited to traditional use and small studies.
How serious is the interaction between Lycopus and Propylthiouracil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining the herb with antithyroid drugs unless supervised. Monitor TSH and free T4 if both are used.
What other medicines interact with Propylthiouracil?
MediHelp also lists interactions of Propylthiouracil with, for example, Carbamazepine, Clozapine, Methimazole. The full list is on the Propylthiouracil page.
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