Interações medicamentosas
Measles mumps rubella and varicella vaccine live + Prednisolone
Gravidade: Contraindicada
Measles mumps rubella and varicella vaccine live and Prednisolone: contraindicated interaction.
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Resumo
This live attenuated combination vaccine can cause disseminated vaccine-strain infection, including varicella, in patients on immunosuppressive doses of prednisolone. The immune response is also reduced.
O que esta interação significa em palavras simples
Measles mumps rubella and varicella vaccine live and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Glucocorticoid immunosuppression impairs control of live attenuated virus replication and blunts the immune response.
O que fazer
Avoid during high-dose steroid therapy and for about one month after stopping, per local guidance. Low-dose or short-course steroids may be acceptable under specialist advice.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Prednisolone
- Bcg vaccine live + Prednisolone Contraindicada
- Measles mumps and rubella vaccine live + Prednisolone Contraindicada
- Measles vaccine + Prednisolone Contraindicada
- Mifepristone + Prednisolone Contraindicada
- Prednisolone + Radium-223 dichloride Contraindicada
- Prednisolone + Rubella vaccine Contraindicada
Perguntas frequentes
Can I take Measles mumps rubella and varicella vaccine live with Prednisolone?
MediHelp rates the interaction as contraindicated. Measles mumps rubella and varicella vaccine live and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated combination vaccine can cause disseminated vaccine-strain infection, including varicella, in patients on immunosuppressive doses of prednisolone. The immune response is also reduced.
How serious is the interaction between Measles mumps rubella and varicella vaccine live and Prednisolone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during high-dose steroid therapy and for about one month after stopping, per local guidance. Low-dose or short-course steroids may be acceptable under specialist advice.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles vaccine. The full list is on the Prednisolone page.
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