Interações medicamentosas
Prednisolone + Rubella vaccine
Gravidade: Contraindicada
Prednisolone and Rubella vaccine: contraindicated interaction.
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Resumo
Rubella vaccine is live attenuated and can replicate excessively in patients on immunosuppressive doses of prednisolone. The immune response may also be reduced.
O que esta interação significa em palavras simples
Prednisolone and Rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Glucocorticoid immunosuppression impairs control of live attenuated virus replication and blunts the immune response.
O que fazer
Avoid during high-dose steroid therapy and for about one month after stopping, per local guidance. Low-dose or short-course steroids may be acceptable under specialist advice.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Prednisolone
- Bcg vaccine live + Prednisolone Contraindicada
- Measles mumps and rubella vaccine live + Prednisolone Contraindicada
- Measles mumps rubella and varicella vaccine live + Prednisolone Contraindicada
- Measles vaccine + Prednisolone Contraindicada
- Mifepristone + Prednisolone Contraindicada
- Prednisolone + Radium-223 dichloride Contraindicada
Perguntas frequentes
Can I take Prednisolone with Rubella vaccine?
MediHelp rates the interaction as contraindicated. Prednisolone and Rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rubella vaccine is live attenuated and can replicate excessively in patients on immunosuppressive doses of prednisolone. The immune response may also be reduced.
How serious is the interaction between Prednisolone and Rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during high-dose steroid therapy and for about one month after stopping, per local guidance. Low-dose or short-course steroids may be acceptable under specialist advice.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Prednisolone page.
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