Interações medicamentosas
Methimazole + Potassium iodide
Gravidade: Moderada
Methimazole and Potassium iodide: moderate interaction.
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Resumo
Both agents reduce thyroid hormone output, and iodide also inhibits hormone release. Together they can produce additive suppression, with a risk of hypothyroidism and goiter if used over a prolonged period. The combination is used deliberately for short periods, for example before thyroid surgery or in thyroid storm.
O que esta interação significa em palavras simples
Methimazole and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Methimazole belongs to Endocrine; Potassium iodide belongs to Endocrine.
Por que acontece
Additive pharmacodynamic suppression of thyroid hormone synthesis and release.
O que fazer
Limit the combination to short, defined courses. Monitor thyroid function and watch for signs of hypothyroidism or goiter if therapy is prolonged.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Methimazole
- Carbamazepine + Methimazole Grave
- Clozapine + Methimazole Grave
- Methimazole + Propylthiouracil Grave
- Methimazole + Sodium iodide i-131 Grave
- Iodinated glycerol + Methimazole Moderada
- Iodine + Methimazole Moderada
Outras interações de Potassium iodide
- Amiloride + Potassium iodide Moderada
- Amlodipine-benazepril + Potassium iodide Moderada
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderada
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderada
- Amlodipine-olmesartan + Potassium iodide Moderada
- Amlodipine-perindopril + Potassium iodide Moderada
Perguntas frequentes
Can I take Methimazole with Potassium iodide?
MediHelp rates the interaction as moderate. Methimazole and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents reduce thyroid hormone output, and iodide also inhibits hormone release. Together they can produce additive suppression, with a risk of hypothyroidism and goiter if used over a prolonged period. The combination is used deliberately for short periods, for example before thyroid surgery or in thyroid storm.
How serious is the interaction between Methimazole and Potassium iodide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit the combination to short, defined courses. Monitor thyroid function and watch for signs of hypothyroidism or goiter if therapy is prolonged.
What other medicines interact with Methimazole?
MediHelp also lists interactions of Methimazole with, for example, Carbamazepine, Clozapine, Propylthiouracil. The full list is on the Methimazole page.
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