Interações medicamentosas
Arsenic trioxide + Moxifloxacin
Gravidade: Contraindicada
Arsenic trioxide and Moxifloxacin: contraindicated interaction.
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Resumo
Arsenic trioxide causes QT prolongation and torsades de pointes and carries a boxed warning. Moxifloxacin adds further QT prolongation, so the combination should be avoided.
O que esta interação significa em palavras simples
Arsenic trioxide and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Arsenic trioxide belongs to Oncology; Moxifloxacin belongs to Anti Bacterial.
Por que acontece
Additive pharmacodynamic QT prolongation.
O que fazer
Avoid the combination and use a non-QT-prolonging antibiotic. If unavoidable, keep potassium and magnesium replete and monitor ECGs frequently.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicada
- Disopyramide + Moxifloxacin Contraindicada
- Dofetilide + Moxifloxacin Contraindicada
- Dronedarone + Moxifloxacin Contraindicada
- Droperidol + Moxifloxacin Contraindicada
- Ibutilide + Moxifloxacin Contraindicada
Outras interações de Arsenic trioxide
- Amiodarone + Arsenic trioxide Contraindicada
- Amisulpride + Arsenic trioxide Contraindicada
- Arsenic trioxide + Clomipramine Contraindicada
- Arsenic trioxide + Dronedarone Contraindicada
- Arsenic trioxide + Fluphenazine Contraindicada
- Arsenic trioxide + Gemifloxacin Contraindicada
Perguntas frequentes
Can I take Arsenic trioxide with Moxifloxacin?
MediHelp rates the interaction as contraindicated. Arsenic trioxide and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Arsenic trioxide causes QT prolongation and torsades de pointes and carries a boxed warning. Moxifloxacin adds further QT prolongation, so the combination should be avoided.
How serious is the interaction between Arsenic trioxide and Moxifloxacin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-QT-prolonging antibiotic. If unavoidable, keep potassium and magnesium replete and monitor ECGs frequently.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Disopyramide, Dofetilide. The full list is on the Moxifloxacin page.
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