Interações medicamentosas
Prednisone + Radium-223 dichloride
Gravidade: Contraindicada
Prednisone and Radium-223 dichloride: contraindicated interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Prednisone is relevant here as the steroid given with abiraterone; that triple combination with radium-223 has shown more fractures and a mortality trend. Prednisone alone with radium-223 is not itself the identified concern.
O que esta interação significa em palavras simples
Prednisone and Radium-223 dichloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Prednisone belongs to Endocrine; Radium-223 dichloride belongs to Miscellaneous.
Por que acontece
The mechanism is not established; additive bone toxicity has been proposed.
O que fazer
Avoid radium-223 in patients receiving abiraterone with prednisone. Review need for steroids and bone protection if used separately.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Prednisone e Radium-223 dichloride, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 7 dias na web. Sem cartão.
Outras interações de Radium-223 dichloride
- Abiraterone + Radium-223 dichloride Contraindicada
- Prednisolone + Radium-223 dichloride Contraindicada
- Radium-223 dichloride + Siponimod Moderada
- Calcium + Radium-223 dichloride Leve
- Radium-223 dichloride + Vitamin d Leve
Outras interações de Prednisone
- Bcg vaccine live + Prednisone Contraindicada
- Measles vaccine + Prednisone Contraindicada
- Mifepristone + Prednisone Contraindicada
- Prednisone + Smallpox vaccine live Contraindicada
- Adenovirus types 4 and 7 live + Prednisone Grave
- Aldesleukin + Prednisone Grave
Perguntas frequentes
Can I take Prednisone with Radium-223 dichloride?
MediHelp rates the interaction as contraindicated. Prednisone and Radium-223 dichloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Prednisone is relevant here as the steroid given with abiraterone; that triple combination with radium-223 has shown more fractures and a mortality trend. Prednisone alone with radium-223 is not itself the identified concern.
How serious is the interaction between Prednisone and Radium-223 dichloride?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid radium-223 in patients receiving abiraterone with prednisone. Review need for steroids and bone protection if used separately.
What other medicines interact with Radium-223 dichloride?
MediHelp also lists interactions of Radium-223 dichloride with, for example, Abiraterone, Prednisolone, Siponimod. The full list is on the Radium-223 dichloride page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
