Лекарственные взаимодействия
Measles mumps rubella and varicella vaccine live + Methylprednisolone
Тяжесть: Противопоказано
Measles mumps rubella and varicella vaccine live and Methylprednisolone: contraindicated interaction.
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Кратко
MMRV contains live attenuated viruses, including varicella, which can disseminate in patients receiving immunosuppressive methylprednisolone. The immune response may also be diminished.
Что означает это взаимодействие простыми словами
Measles mumps rubella and varicella vaccine live and Methylprednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Почему это происходит
Corticosteroid-induced suppression of cell-mediated immunity permits uncontrolled replication of live vaccine viruses.
Что делать
Do not administer during immunosuppressive steroid doses; postpone until steroids have been stopped for the recommended interval. Separate MMR and varicella vaccines are not safer, so use the same deferral.
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Другие взаимодействия Methylprednisolone
- Bcg vaccine live + Methylprednisolone Противопоказано
- Measles mumps and rubella vaccine live + Methylprednisolone Противопоказано
- Measles vaccine + Methylprednisolone Противопоказано
- Methylprednisolone + Mifepristone Противопоказано
- Methylprednisolone + Rubella vaccine Противопоказано
- Methylprednisolone + Smallpox vaccine live Противопоказано
Частые вопросы
Can I take Measles mumps rubella and varicella vaccine live with Methylprednisolone?
MediHelp rates the interaction as contraindicated. Measles mumps rubella and varicella vaccine live and Methylprednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMRV contains live attenuated viruses, including varicella, which can disseminate in patients receiving immunosuppressive methylprednisolone. The immune response may also be diminished.
How serious is the interaction between Measles mumps rubella and varicella vaccine live and Methylprednisolone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer during immunosuppressive steroid doses; postpone until steroids have been stopped for the recommended interval. Separate MMR and varicella vaccines are not safer, so use the same deferral.
What other medicines interact with Methylprednisolone?
MediHelp also lists interactions of Methylprednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles vaccine. The full list is on the Methylprednisolone page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.
