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Лекарственные взаимодействия

Measles vaccine + Methylprednisolone

Тяжесть: Противопоказано

Measles vaccine and Methylprednisolone: contraindicated interaction.

Последнее обновление

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Кратко

Measles vaccine is live attenuated, and immunosuppressive doses of methylprednisolone may cause vaccine-virus replication and disease while also impairing the response. This is a recognized precaution in vaccine labeling.

Что означает это взаимодействие простыми словами

Measles vaccine and Methylprednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Уровень доказательности: High

Почему это происходит

Corticosteroid-induced suppression of cellular immunity reduces control of live attenuated virus.

Что делать

Do not give live measles vaccine during immunosuppressive steroid doses. Defer until the steroid has been stopped for the interval in local guidance, usually at least one month for high-dose therapy.

О чём спросить фармацевта

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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Частые вопросы

Can I take Measles vaccine with Methylprednisolone?

MediHelp rates the interaction as contraindicated. Measles vaccine and Methylprednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated, and immunosuppressive doses of methylprednisolone may cause vaccine-virus replication and disease while also impairing the response. This is a recognized precaution in vaccine labeling.

How serious is the interaction between Measles vaccine and Methylprednisolone?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live measles vaccine during immunosuppressive steroid doses. Defer until the steroid has been stopped for the interval in local guidance, usually at least one month for high-dose therapy.

What other medicines interact with Methylprednisolone?

MediHelp also lists interactions of Methylprednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Methylprednisolone page.

Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp

Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.

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