藥品參考
Brincidofovir
Brincidofovir is a medicine in the class anti virals.
- 藥物類別: Anti Virals
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Virals
- 常見劑型
- 錠劑, 口服懸液
- 商品名
- 1
- 國家與市場
- 1
作用方式
Orthopoxvirus nucleotide analog DNA polymerase inhibitor; antiviral against variola (smallpox) virus. Prodrug converted intracellularly to cidofovir, then phosphorylated to the active cidofovir diphosphate.
成人常用劑量（仿單摘要）
Smallpox: patients weighing 48 kg and above: 200 mg (two 100 mg tablets or 20 mL oral suspension), oral, once weekly for 2 doses (Days 1 and 8)
懷孕與哺乳
- 懷孕
- Unsafe May cause fetal harm based on animal studies; no human data; use alternative therapy during pregnancy if feasible.
- 哺乳
- Unsafe Breastfeeding not recommended in patients with smallpox because of variola transmission risk; no data on brincidofovir in human milk.
已通報的副作用
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
黑框警語
- Increased mortality was seen in TEMBEXA-treated subjects compared with placebo in a 24-week clinical trial in another disease; risk of mortality increased when used for longer duration.
禁忌症
- None
哪些人需要特別留意
- Increased mortality possible if used longer than the recommended Days 1 and 8 regimen; not indicated for diseases other than smallpox
- Elevations in ALT, AST and bilirubin; severe hepatobiliary events reported in less than 1%; monitor liver tests
- Diarrhea and other GI adverse events including nausea, vomiting, abdominal pain; monitor for dehydration
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Brincidofovir 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Brincidofovir used for?
Brincidofovir is a medicine in the class anti virals.
What side effects have been reported with Brincidofovir?
Diarrhea, Nausea, Vomiting, Abdominal pain. Serious warning: Increased mortality was seen in TEMBEXA-treated subjects compared with placebo in a 24-week clinical trial in another disease; risk of mortality increased when used for longer duration.
Can Brincidofovir be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause fetal harm based on animal studies; no human data; use alternative therapy during pregnancy if feasible. Breastfeeding: Unsafe. Breastfeeding not recommended in patients with smallpox because of variola transmission risk; no data on brincidofovir in human milk.
What does Brincidofovir interact with?
MediHelp does not list a checked interaction for Brincidofovir yet. Always tell your pharmacist about every medicine you take.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
