藥品參考
Trifluridine
Trifluridine is a medicine in the class anti virals. It is used for herpes simplex.
- 藥物類別: Anti Virals
- 用途: herpes simplex
最後更新 來源: US FDA label
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Virals
用途
作用方式
Trifluridine is a fluorinated pyrimidine nucleoside active against herpes simplex virus types 1 and 2. It interferes with DNA synthesis in cultured mammalian cells, but its antiviral mechanism of action is not completely known.
懷孕與哺乳
- 懷孕
- Unsafe Eye drops: little is absorbed; fetal loss only with high injected doses in animals; use only if needed. Oral tablets with tipiracil (Lonsurf, for cancer): can cause fetal harm (fetal deaths in rats at human exposure); avoid and use contraception.
- 哺乳
- Unsafe Eye drops: little is expected in milk; US label: weigh benefits; no LactMed record. Oral tablets with tipiracil (Lonsurf): do not breastfeed during treatment and for 1 day after the last dose.
已通報的副作用
- Burning or stinging upon instillation
- Palpebral edema
- Superficial punctate keratopathy
- Epithelial keratopathy
- Hypersensitivity reaction
- Stromal edema
禁忌症
- Patients who develop hypersensitivity reactions or chemical intolerance to trifluridine.
哪些人需要特別留意
- The recommended dosage and frequency should not be exceeded.
- Prescribe only for patients with a clinical diagnosis of herpetic keratitis.
- May cause mild, usually transient local irritation of the conjunctiva and cornea.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
同類別的其他藥品
常見問題
What is Trifluridine used for?
Trifluridine is a medicine in the class anti virals. It is used for Herpes simplex, Herpetic keratitis.
What side effects have been reported with Trifluridine?
Burning or stinging upon instillation, Palpebral edema, Superficial punctate keratopathy, Epithelial keratopathy, Hypersensitivity reaction, Stromal edema.
Can Trifluridine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Eye drops: little is absorbed; fetal loss only with high injected doses in animals; use only if needed. Oral tablets with tipiracil (Lonsurf, for cancer): can cause fetal harm (fetal deaths in rats at human exposure); avoid and use contraception. Breastfeeding: Unsafe. Eye drops: little is expected in milk; US label: weigh benefits; no LactMed record. Oral tablets with tipiracil (Lonsurf): do not breastfeed during treatment and for 1 day after the last dose.
What does Trifluridine interact with?
MediHelp does not list a checked interaction for Trifluridine yet. Always tell your pharmacist about every medicine you take.
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