藥品參考
Difamilast
Difamilast is a medicine in the class respiratory. It is used for atopic dermatitis.
- 藥物類別: Respiratory
- 用途: atopic dermatitis
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Respiratory
- 常見劑型
- 軟膏
- 常見規格
- 10 mg/g
- 商品名
- 1
- 國家與市場
- 1
用途
作用方式
Difamilast inhibits phosphodiesterase-4 (PDE-4), leading to accumulation of intracellular cyclic AMP and decreased production of various cytokines and chemokines. The specific mechanism of therapeutic action is not well defined.
成人常用劑量（仿單摘要）
Mild to moderate atopic dermatitis: apply a thin layer topically twice daily to affected areas and rub in completely
懷孕與哺乳
- 懷孕
- Unknown Ointment for atopic dermatitis. Human data are insufficient; in animals, fetal effects occurred only with under-the-skin doses far above human exposure (about 14 times or more). Use only if needed, on limited areas.
- 哺乳
- Unknown No human milk data; in rats it passed into milk at levels above blood. Topical use gives low exposure. Do not apply to the nipple or areola; weigh breastfeeding against the need for treatment.
已通報的副作用
- Nasopharyngitis
- Application site folliculitis
- Contact dermatitis
- Application site rash
- Application site swelling
禁忌症
- None listed in the US prescribing information (section 4 Contraindications: "None"; Adquey, DailyMed set id 46c95e41-fa29-4e11-9d94-0fd4f0291c34).
哪些人需要特別留意
- Avoid applying to infected skin areas.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
同類別的其他藥品
常見問題
What is Difamilast used for?
Difamilast is a medicine in the class respiratory. It is used for Atopic dermatitis.
What side effects have been reported with Difamilast?
Nasopharyngitis, Application site folliculitis, Contact dermatitis, Application site rash, Application site swelling.
Can Difamilast be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Ointment for atopic dermatitis. Human data are insufficient; in animals, fetal effects occurred only with under-the-skin doses far above human exposure (about 14 times or more). Use only if needed, on limited areas. Breastfeeding: Unknown. No human milk data; in rats it passed into milk at levels above blood. Topical use gives low exposure. Do not apply to the nipple or areola; weigh breastfeeding against the need for treatment.
What does Difamilast interact with?
MediHelp does not list a checked interaction for Difamilast yet. Always tell your pharmacist about every medicine you take.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
