藥品參考
Doripenem
Doripenem is a medicine in the class anti bacterial. It is used for intra-abdominal infections.
- 藥物類別: Anti Bacterial
- 用途: intra-abdominal infections
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Bacterial
- 已知交互作用
- 1 (中度: 1)
用途
作用方式
Inhibits cell-wall biosynthesis by inactivating multiple penicillin-binding proteins (PBPs), resulting in cell death. Stable to hydrolysis by most beta-lactamases
成人常用劑量（仿單摘要）
Complicated Intra-abdominal Infection: 500 mg IV infusion over 1 hour q8hr x 5-14 days
懷孕與哺乳
- 懷孕
- Unknown Limited human data; animal studies showed no harm. Doripenem is no longer marketed in the US. Carbapenems are used in pregnancy for serious infections when needed; meropenem has more experience.
- 哺乳
- Safe No direct data, but other carbapenems (imipenem, meropenem) pass into milk in low amounts. LactMed: acceptable while breastfeeding; watch the infant for diarrhoea or thrush.
已通報的副作用
- Headache
- Diarrhea
- Nausea
- Rash
- Pruritus
- Anemia
禁忌症
- Hypersensitivity to doripenem, beta-lactams or similar drugs
哪些人需要特別留意
- Caution with history of sensitivity to multiple allergens
- Seizures reported with use
- May reduce serum valproic acid conc to subtherapeutic level: monitor levels frequently
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (1)
- Doripenem + Microbiota Moderate
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Doripenem 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Doripenem used for?
Doripenem is a medicine in the class anti bacterial. It is used for Intra-abdominal infections, Urinary tract infections.
What side effects have been reported with Doripenem?
Headache, Diarrhea, Nausea, Rash, Pruritus, Anemia.
Can Doripenem be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data; animal studies showed no harm. Doripenem is no longer marketed in the US. Carbapenems are used in pregnancy for serious infections when needed; meropenem has more experience. Breastfeeding: Safe. No direct data, but other carbapenems (imipenem, meropenem) pass into milk in low amounts. LactMed: acceptable while breastfeeding; watch the infant for diarrhoea or thrush.
What does Doripenem interact with?
MediHelp lists 1 known interactions for Doripenem. Moderate: 1. The most serious include Microbiota.
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