藥品參考
Exemestane
Exemestane is a medicine in the class oncology. It is used for breast cancer.
- 藥物類別: Oncology
- 用途: breast cancer
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Oncology
- 常見劑型
- 錠劑
- 常見規格
- 25 mg
- 已知交互作用
- 66 (嚴重: 13 · 中度: 32 · 輕微: 21)
- 商品名
- 10
- 國家與市場
- 4
用途
作用方式
Aromatase inhibitor - blocks conversion of androgens to estrogens by binding to the heme group of aromatase enzyme, which in turn inhibits its activity
成人常用劑量(仿單摘要)
Advanced disease: 25 mg PO qDay; continue until tumor progression
懷孕與哺乳
- 懷孕
- Unsafe Can cause fetal harm (animal studies); it is for postmenopausal women only. Contraindicated in pregnancy (EU label). Check pregnancy status before starting in women who could conceive and use effective contraception during treatment and for 1 month after the last dose.
- 哺乳
- Unsafe No human milk data. Most sources say do not breastfeed during cancer treatment; the US label advises not to breastfeed during treatment and for 1 month after the last dose.
已通報的副作用
- Fatigue
- Nausea
- Insomnia
- Hot flashes
- Pain
- Depression
哪些人需要特別留意
- Not indicated for breast cancer in premenopausal women
- Advise females of reproductive potential to use effective contraception during treatment and for 1 month after final dose
- Based on findings in animals, male and female fertility may be impaired by treatment
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。
重要交互作用 (66)
- Bazedoxifene-conjugated estrogens + Exemestane Major
- Desogestrel-ethinyl estradiol + Exemestane Major
- Estradiol + Exemestane Major
- Estrogens conjugated synthetic + Exemestane Major
- Estrogens esterified + Exemestane Major
- Estropipate + Exemestane Major
- Ethinyl estradiol-drospirenone + Exemestane Major
- Ethinyl estradiol-levonorgestrel + Exemestane Major
- Ethinylestradiol + Exemestane Major
- Exemestane + Mitotane Major
同類別的其他藥品
相關快速閱讀
常見問題
What is Exemestane used for?
Exemestane is a medicine in the class oncology. It is used for Breast cancer.
What side effects have been reported with Exemestane?
Fatigue, Nausea, Insomnia, Hot flashes, Pain, Depression.
Can Exemestane be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Can cause fetal harm (animal studies); it is for postmenopausal women only. Contraindicated in pregnancy (EU label). Check pregnancy status before starting in women who could conceive and use effective contraception during treatment and for 1 month after the last dose. Breastfeeding: Unsafe. No human milk data. Most sources say do not breastfeed during cancer treatment; the US label advises not to breastfeed during treatment and for 1 month after the last dose.
What does Exemestane interact with?
MediHelp lists 66 known interactions for Exemestane. Major: 13 · Moderate: 32 · Minor: 21. The most serious include Bazedoxifene-conjugated estrogens, Desogestrel-ethinyl estradiol, Estradiol.
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