藥品參考
Marstacimab
Marstacimab is a medicine in the class cardiovascular. It is used for hemophilia a.
- 藥物類別: Cardiovascular
- 用途: hemophilia a
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Cardiovascular
- ATC 代碼
- B02BX11
- 常見劑型
- 注射劑
- 已知交互作用
- 1 (嚴重: 1)
- 商品名
- 2
- 國家與市場
- 2
用途
作用方式
Human monoclonal IgG1 antibody directed against Kunitz domain 2 (K2) of TFPI that neutralizes TFPI activity and enhances coagulation.
成人常用劑量（仿單摘要）
Routine prophylaxis in hemophilia A or B, adults and patients 12 years and older: loading dose 300 mg (two 150 mg injections) subcutaneous once
懷孕與哺乳
- 懷孕
- Unsafe May cause fetal harm based on how it works (it blocks a natural anticoagulant, TFPI); no human data and no animal reproduction studies. Antibodies cross the placenta. Use effective contraception during treatment and for 2 months after the last dose.
- 哺乳
- Unknown No data on passage into milk. As a large antibody, milk levels are likely very low and poorly absorbed. LactMed: use with caution, especially with a newborn or preterm infant; waiting 2 weeks after birth may reduce transfer.
已通報的副作用
- Injection site reaction
- Headache
- Pyrexia
- Arthralgia
- Diarrhea
- Pruritus
禁忌症
- None.
哪些人需要特別留意
- Thromboembolic events may occur; interrupt prophylaxis if findings consistent with thromboembolism occur. Not studied in patients with prior thromboembolic events.
- Hypersensitivity reactions (including urticaria and pruritus) may occur; discontinue and seek emergency treatment if severe.
- May cause fetal harm; advise effective contraception during treatment and for 2 months after last dose.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (1)
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Marstacimab 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Marstacimab used for?
Marstacimab is a medicine in the class cardiovascular. It is used for Hemophilia a, Hemophilia b.
What side effects have been reported with Marstacimab?
Injection site reaction, Headache, Pyrexia, Arthralgia, Diarrhea, Pruritus.
Can Marstacimab be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause fetal harm based on how it works (it blocks a natural anticoagulant, TFPI); no human data and no animal reproduction studies. Antibodies cross the placenta. Use effective contraception during treatment and for 2 months after the last dose. Breastfeeding: Unknown. No data on passage into milk. As a large antibody, milk levels are likely very low and poorly absorbed. LactMed: use with caution, especially with a newborn or preterm infant; waiting 2 weeks after birth may reduce transfer.
What does Marstacimab interact with?
MediHelp lists 1 known interactions for Marstacimab. Major: 1. The most serious include Factor viii.
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