藥品參考
Pemetrexed
Pemetrexed is a medicine in the class oncology. It is used for lung cancer.
- 藥物類別: Oncology
- 用途: lung cancer
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Oncology
- ATC 代碼
- L01BA04
- 常見劑型
- 注射劑, 輸注液, 溶液
- 常見規格
- 500 mg, 25 mg/ml, 100 mg
- 已知交互作用
- 58 (嚴重: 32 · 中度: 22 · 輕微: 4)
- 商品名
- 33
- 國家與市場
- 5
用途
作用方式
Antifolate antineoplastic agent: Disrupts folate-dependent metabolic processes essential for cell replication
成人常用劑量（仿單摘要）
Mesothelioma: In combination with cisplatin: Pemetrexed 500 mg/m2 IV on Day 1 of each 21-day cycle until disease progression or unacceptable toxicity.
懷孕與哺乳
- 懷孕
- Unsafe Can cause fetal harm: teratogenic in mice at doses below the human dose; it is an antifolate. No human data. Avoid; check pregnancy status and use contraception during treatment and for 6 months after the last dose (men: 3 months).
- 哺乳
- Unsafe No data on milk levels. Because of possible serious infant reactions, do not breastfeed during treatment and for 1 week after the last dose. LactMed: breastfeeding is generally contraindicated during high-dose chemotherapy.
已通報的副作用
- Fatigue
- Vomiting
- Nausea
- Anemia
- Neutropenia
- Thrombocytopenia
哪些人需要特別留意
- Radiation recall can occur in patients who have received radiation weeks to years previously
- Based on findings from animal studies and its mechanism of action, therapy can cause fetal harm when administered to a pregnant woman; avoid pregnancy
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (58)
- Bacitracin + Pemetrexed Major
- Brexucabtagene autoleucel + Pemetrexed Major
- Celecoxib + Pemetrexed Major
- Ciltacabtagene autoleucel + Pemetrexed Major
- Deferiprone + Pemetrexed Major
- Dengue vaccine + Pemetrexed Major
- Diclofenac + Pemetrexed Major
- Diflunisal + Pemetrexed Major
- Etodolac + Pemetrexed Major
- Etrasimod + Pemetrexed Major
同類別的其他藥品
常見問題
What is Pemetrexed used for?
Pemetrexed is a medicine in the class oncology. It is used for Lung cancer, Mesothelioma.
What side effects have been reported with Pemetrexed?
Fatigue, Vomiting, Nausea, Anemia, Neutropenia, Thrombocytopenia.
Can Pemetrexed be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Can cause fetal harm: teratogenic in mice at doses below the human dose; it is an antifolate. No human data. Avoid; check pregnancy status and use contraception during treatment and for 6 months after the last dose (men: 3 months). Breastfeeding: Unsafe. No data on milk levels. Because of possible serious infant reactions, do not breastfeed during treatment and for 1 week after the last dose. LactMed: breastfeeding is generally contraindicated during high-dose chemotherapy.
What does Pemetrexed interact with?
MediHelp lists 58 known interactions for Pemetrexed. Major: 32 · Moderate: 22 · Minor: 4. The most serious include Bacitracin, Brexucabtagene autoleucel, Celecoxib.
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